As we get older, our bodies face numerous transformations that result in poor energy, impairment of the mental realm, and higher chances of being afflicted by age-related ailments. But what if it was possible to mitigate the consequences of old age or even add years back to one’s life? Nicotinamide mononucleotide (NMN), a molecular compound that has sparked controversy in anti-aging studies.
What is NMN?
NMN is a precursor of NAD+ (nicotinamide adenine dinucleotide), which is considered as one of the most important molecules that maintains the cellular energy and health. With increasing age, there has also been a natural decrease in levels of Nad. This decline is likely to play a role in aiding the aging process. NMN supplementation is thought to boost the levels of Nad and therefore, help in extending healthspan.
The Promise of NMN
There are far more reasons than the chronic diseases of aging that excite even in animals with whom NMN supplementation has shown potential benefits:
- Increased metabolic rate and better insulin action
- Cardiovascular support
- Intellectual and neuroprotective improvement.
- Enhanced energy levels and physical fitness
- Vision enhancement
These results created a greater understanding of the NMN as potential prevention drugs for the aging process in people.
Research Trends
Although considerable evidence is available from animal studies, the research into humans on NMN stays at an infant stage. The results from these recently conducted few small clinical trials indicate that the NMN supplementation is reasonably well tolerated and appears to be safe in humans with some evidence of metabolic improvements, if any. Nevertheless, further research designed as such may eventually lead to a clearer picture on, and characterization of, NMN physiological effects and appropriate NMN doses in humans.
Safety Considerations
The human NMN treatment attaches very minimal risk based on prior studies, but those studies did not consider some important factors;
- Effects in humans on long term usage are still unknown
- Risk of interaction with other pharmacological preparations is yet to be systematically addressed
- The best dose for human consumption is yet to be determined
- Available single-use supplements may vary in potency and composition
The Bottom Line
NMN appears to have beneficial effects as an anti-aging supplement. However, the further investigations are warranted to enable definite evaluation of NMN benefits to humans, especially on the risks and safety. If you want to take NMN, consult your healthcare provider, just like you would for any health product, especially if you have health problems or are on any treatment.
As new studies advance, it will be easier to determine the extent to which NMN may be utilized to age well. So far, it stays an interesting molecule that emphasizes the enjoyable areas of research into aging.
Needless to say, although NMN and similar supplements cause some positive effects, they will never replace a healthy diet and lifestyle as such. Eating the right foods, exercising, spending less time in stressful situations and receiving adequate rest is the basis of what makes a person age graciously.
