Researchers have made an exciting discovery about how advanced chelate technology-based trace minerals can help protect chickens from the harmful effects of coccidiosis, a common parasitic infection. The study found that completely replacing conventional inorganic trace minerals with this new chelated formula not only improved the chickens’ growth and feed efficiency, but also reduced inflammation and oxidative stress in the gut. This is achieved by modulating the activity of key cellular pathways like NF-κB and Nrf2. This breakthrough could pave the way for better nutritional solutions to support the health and productivity of poultry flocks.
Combating the Harmful Effects of Coccidiosis
Coccidiosis is a highly contagious and debilitating parasitic infection that affects poultry, causing significant economic losses for farmers. The invasion of Eimeria species, the causative agents of coccidiosis, can disrupt the normal functioning of the chicken’s intestines, leading to inflammation and oxidative stress. This in turn impairs nutrient absorption, growth, and overall health of the birds.
The Power of Advanced Trace Minerals
Trace minerals like zinc, copper, manganese, and iron play crucial roles in the body’s antioxidant defenses and immune response. Traditionally, poultry farmers have relied on inorganic forms of these minerals as dietary supplements. However, the researchers in this study explored the use of an innovative “advanced chelate technology-based” trace mineral (ACTM) supplement.
Modulating Key Cellular Pathways
The study found that completely replacing inorganic trace minerals with the ACTM supplement was able to effectively protect chickens from the harmful effects of the Eimeria challenge. This was achieved by modulating the activity of two important cellular pathways:
1. NF-κB pathway: ACTM supplementation reduced the expression of pro-inflammatory cytokines like IL-1β and IL-6, thereby dampening the inflammatory response.
2. Nrf2 pathway: ACTM also enhanced the activity of antioxidant enzymes like peroxidase’>glutathione peroxidase, helping to neutralize the oxidative stress caused by the Eimeria infection.
Improved Growth and Productivity
The study demonstrated that chickens receiving the complete ACTM supplement exhibited better growth performance, feed efficiency, and carcass yields compared to those fed the conventional inorganic trace minerals. The ACTM group also showed higher levels of beneficial gut bacteria like Lactobacillus, as well as improved mineral absorption and antioxidant status.
Promising Implications for Poultry Health
This breakthrough in trace mineral supplementation could have significant implications for the poultry industry. By mitigating the harmful effects of coccidiosis through modulation of key cellular pathways, the ACTM supplement has the potential to improve the health, productivity, and overall well-being of broiler chickens. Further research is needed to optimize the dosage and long-term benefits of this innovative approach.
Author credit: This article is based on research by Nasim Biabani, Kamran Taherpour, Hossein Ali Ghasemi, Mohammad Akbari Gharaei, Maryam Hafizi, Mohammad Hassan Nazaran.
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