A new study has found that mindfulness-based stress reduction (MBSR) is just as effective as the leading antidepressant, escitalopram, in treating various anxiety disorders. The research suggests that mindfulness practices could provide a viable, side-effect-free option for managing conditions like agoraphobia, panic disorder, generalized anxiety disorder, and social anxiety disorder.

Mindfulness Rivals Antidepressants in Treating Anxiety
The groundbreaking study, led by the National Institute of Mental Health, has revealed that mindfulness-based stress reduction (MBSR) can be just as effective as the commonly prescribed antidepressant escitalopram (sold as Lexapro and Cipralex) in reducing the symptoms of various anxiety disorders.
Anxiety disorders affect millions of people worldwide and are often treated with selective serotonin reuptake inhibitors (SSRIs) like escitalopram. While these medications can be helpful in managing the symptoms, they also come with a host of side effects that can negatively impact a patient’s quality of life, including nausea, headaches, dry mouth, excessive sweating, insomnia, and fatigue.
Mindfulness: A Safer Alternative to Anxiety Medications
The research team previously demonstrated that eight weeks of mindfulness-based stress reduction was just as effective as escitalopram in providing stress relief and emotional regulation, without the additional drawbacks. In this new study, they delved deeper, examining the secondary outcomes of patient-reported anxiety, depression, and quality of life.
The study involved 276 adults diagnosed with various anxiety disorders, who were randomly assigned to either the MBSR program or escitalopram treatment. The MBSR group attended weekly sessions focused on mindfulness meditation techniques, while the escitalopram group received dosages ranging from 10 to 20 mg per day with regular clinical follow-ups. Researchers used standardized scales to measure anxiety, depression, and quality of life from both patient and clinician perspectives.
Mindfulness Offers Significant Benefits with Fewer Risks
The findings revealed that both the MBSR and escitalopram groups experienced similar reductions in anxiety symptoms over the study period. While escitalopram showed a slight edge in symptom reduction at the midtreatment point (week 4), these improvements were not sustained by the end of the study.
The most significant difference between the two treatments was the rate of adverse events. Nearly 79% of escitalopram recipients reported at least one study-related side effect, compared to just 15% of those in the mindfulness group. This suggests that mindfulness-based stress reduction can be a reliable, safer alternative for treating anxiety disorders, with the potential for broader application in clinical settings.