Air pollution is a major environmental challenge that poses serious threats to human health globally. A recent study has shed light on the substantial burden of mortality attributed to fine particulate matter (PM2.5) pollution in Mashhad, Iran’s second-largest city. Using the World Health Organization’s AirQ+ software, the researchers analyzed the long-term health impacts of PM2.5 exposure in Mashhad from 2016 to 2021. The findings reveal a concerning rise in deaths from various causes, including ischemic heart disease, stroke, chronic obstructive pulmonary disease, and lung cancer, underscoring the urgent need for effective air quality management policies to protect public health. This research highlights the importance of quantifying the health burden of air pollution to inform policymakers and drive action towards cleaner air.

Alarming Levels of Air Pollution in Mashhad
Mashhad, a city in northeastern Iran with a population of over 3 million, has been grappling with significant air pollution challenges. The study found that the annual average concentrations of fine particulate matter (PM2.5) in Mashhad consistently exceeded the World Health Organization’s (WHO) recommended limit of 5 micrograms per cubic meter (μg/m³) during the 2016-2021 period. In fact, the highest annual average was recorded in 2021 at 35.13 μg/m³, more than seven times the WHO guideline.
Quantifying the Health Burden of PM2.5 Exposure
To assess the impact of this air pollution, the researchers utilized the WHO’s AirQ+ software, a tool designed to quantify the health effects of exposure to various air pollutants. The analysis revealed a substantial burden of mortality associated with long-term PM2.5 exposure in Mashhad:
– All-Cause Mortality: The number of deaths from all natural causes attributed to PM2.5 exposure increased from 2,093 [95% confidence interval: 1,627-2,314] in 2016 to 2,750 [2,139-3,038] in 2021.
– Ischemic Heart Disease: The number of deaths from ischemic heart disease linked to PM2.5 exposure more than doubled, from 244 [144-290] in 2016 to 445 [295-592] in 2021.
– Stroke: The mortality burden from stroke associated with PM2.5 exposure increased from 150 [111-192] deaths in 2016 to 239 [179-299] deaths in 2021.
– Chronic Obstructive Pulmonary Disease (COPD): The number of COPD deaths attributable to PM2.5 exposure rose from 49 [36-61] in 2016 to 68 [50-85] in 2021.
– Lung Cancer: While the total number of lung cancer deaths remained relatively stable, the mortality burden linked to PM2.5 exposure was 46 [33-59] deaths in 2016 and 48 [34-61] deaths in 2021.
Implications and Recommendations
The findings of this study highlight the significant and growing health burden associated with air pollution in Mashhad. The researchers emphasize that these results can inform policymakers and drive the implementation of effective strategies to improve air quality and protect public health.
Some key implications and recommendations from the study include:
– Urgent Need for Air Quality Management: The consistently high levels of PM2.5 in Mashhad call for immediate action to implement robust air pollution control measures, such as reducing emissions from transportation, industry, and other sources.
– Prioritizing Vulnerable Populations: The study identified increased mortality risks in specific age groups, underscoring the importance of targeted interventions to protect the most vulnerable, such as the elderly and young children.
– Integrating Health Impact Assessments: Incorporating air pollution health impact assessments into policymaking frameworks can help guide decision-making and measure the effectiveness of mitigation strategies.
By quantifying the substantial health burden of air pollution in Mashhad, this research provides a strong scientific basis to drive environmental policy reforms and improve public health outcomes in the region.
Tackling a Global Challenge
The findings from Mashhad are not unique, as air pollution remains a global public health crisis. According to the World Health Organization, air pollution exposure is responsible for around 7 million premature deaths worldwide each year. Addressing this challenge requires concerted efforts at the local, national, and international levels to implement evidence-based policies and promote sustainable development.
Towards Cleaner Air and Healthier Communities
The Mashhad study serves as a valuable case study, highlighting the importance of using tools like the AirQ+ software to quantify the health impacts of air pollution. By providing policymakers with robust data on the burden of disease, this research can inform the development of targeted strategies to improve air quality and protect public health. As the global community continues to grapple with the complex issue of air pollution, studies like this one offer critical insights and a pathway towards healthier and more sustainable communities.
Author credit: This article is based on research by Nayera Naimi, Maryam Sarkhosh, Bibi Fatemeh Nabavi, Aliasghar Najafpoor, Ehsan Musa Farkhani.
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